Posology: Airtal film-coated tablets are supplied for oral administration.
When Airtal was administration to fasting and fed healthy volunteers, only the rate but not the extent absorption of aceclofenac was affected.
Undesirable effected maybe minimised by using the lowest effective dose for the shortest duration necessary to control symptom (see Precautions).
Adults: The recommended dose is 200 mg daily, taken as two separate 100 mg dose, one tablet in the morning and one in the evening.
Paediatric population: There are no clinical data for use of Airtal in children and therefore it is not recommended for use in children.
Elderly: The elderly, who are more likely to be suffering from impaired renal, cardiovascular or hepatic function and receiving concomitant medication, are at increased risk of the serious consequences of adverse reactions. If an NSAID is considered necessary, the lowest effective dose should be used and for the shortest possible duration. The patient should be monitored regularly for GI bleeding during NSAID therapy.
The pharmacokinetics of Airtal are not altered in elderly patients, therefore it is not considered necessary to modify the dose or dose frequency.
Renal insufficiency: There is no evidence that the dosage of Airtal needs to be modified in patients with mild renal impairment, but as with other NSAIDs caution should be exercised (see also Precautions).
Hepatic insufficiency: There is some evidence that the dose of Airtal should be reduced in patients with hepatic impairment and it is suggested that an initial daily dose of 100 mg be used.
Method of administration: To be taken preferably with or after food. The tablets should be swallowed whole with a sufficient quantity of liquid.
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