Caution: A sterile syringe free of preservatives, antiseptics, and detergents should be used for each injection and/or reconstitution of refrigerator-stable VARIVAX because these substances may inactivate the vaccine virus.
It is important to use a separate sterile syringe and needle for each patient to prevent transmission of infectious agents from one individual to another.
To reconstitute the vaccine, use only the Merck sterile diluent supplied with refrigerator-stable VARIVAX, since it is free of preservatives or other anti-viral substances which might inactivate the vaccine virus.
Do not freeze reconstituted vaccine.
Do not give immune globulin, including Varicella Zoster Immune Globulin, concurrently with refrigerator-stable VARIVAX (see also Precautions).
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Refrigerator-stable VARIVAX when reconstituted is a clear, colorless to pale yellow liquid.
Stability: Refrigerator-stable VARIVAX has a minimum potency level of approximately 1350 PFU 30 minutes after reconstitution at room temperature (20 to 25°C, 68 to 77°F).