Zyvox Dosage/Direction for Use

General Dosage and Administration: The recommended dosage for linezolid (ZYVOX) formulations for the treatment of infections is described in Table 11. (See Table 11.)

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No dose adjustment is necessary when switching from intravenous to oral administration.
Intravenous Administration: Linezolid (ZYVOX) Solution for Infusion (IV) is supplied in single dose, ready-to-use infusion bags. Parenteral drug products should be inspected visually for particulate matter prior to administration. Check for minute leaks by firmly squeezing the bag. If leaks are detected, discard the solution, as sterility may be impaired. Keep the infusion bags in the overwrap until ready to use. Store at room temperature. Protect from freezing. Linezolid (ZYVOX) Solution for Infusion (IV) may exhibit a yellow color that can intensify over time without adversely affecting potency.
Linezolid (ZYVOX) Solution for Infusion (IV) should be administered by intravenous infusion over a period of 30 to 120 minutes. Do not use this intravenous infusion bag in series connections. Additives should not be introduced into this solution. If linezolid (ZYVOX) Solution for Infusion (IV) is to be given concomitantly with another drug, each drug should be given separately in accordance with the recommended dosage and route of administration for each product. Discard unused portion.
If the same intravenous line is used for sequential infusion of several drugs, the line should be flushed before and after infusion of linezolid (ZYVOX) Solution for Infusion (IV) with an infusion solution compatible with linezolid (ZYVOX) Solution for Infusion (IV) and with any other drug(s) administered via this common line.