Zyphrine Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Levocetirizine HCl

Indications/Uses

Relief of nasal & ocular symptoms of seasonal & perennial allergic rhinitis. Relief of symptoms of chronic idiopathic urticaria.

Click to view Zyphrine detailed prescribing information

Dosage/Direction for Use

Adult & childn ≥12 yr 2 tsp (10 mL). Childn 6-11 yr 1 tsp (5 mL); 6 mth to 5 yr 1.25 mg (2.5 mL). All doses are taken once daily in the evening. Renal impairment CrCl ≥80 mL/min 5 mg once daily; 50-79 mL/min 5 mg once daily; 30-49 mL/min 5 mg once every 2 days; <30 mL/min 5 mg once every 3 days.

Click to view Zyphrine detailed prescribing information

Overdosage

View Zyphrine overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food: Take in the evening.

Contraindications

Hypersensitivity to levocetirizine or other piperazine derivatives. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Severe renal impairment (CrCl <10 mL/min). Childn 6 mth-11 yr w/ renal impairment.

Click to view Zyphrine detailed prescribing information

Special Precautions

Epileptic patients & patients at risk of convulsions. Avoid concurrent use w/ alcohol or other CNS depressants. Patients w/ predisposing factors of urinary retention (eg, spinal cord lesion, prostatic hyperplasia); discontinue if urinary retention occurs. May impair ability to drive or operate machines. Pregnancy & lactation. Not recommended in infant & toddlers <2 yr.

Click to view Zyphrine detailed prescribing information

Use In Pregnancy & Lactation

Click to view Zyphrine detailed prescribing information

Adverse Reactions

Headache, somnolence, mouth dryness, fatigue, hypersensitivity including anaphylaxis, aggression, agitation, convulsion, visual disturbances, palpitation, dyspnoea, nausea, hepatitis, angioneurotic oedema, fixed drug eruption, pruritus, rash & urticaria.

Click to view Zyphrine detailed prescribing information

Drug Interactions

Decreased clearance w/ theophylline. May have CNS effects w/ alcohol or other CNS depressants.

Click to view Zyphrine detailed prescribing information

Storage

View Zyphrine storage conditions for details to ensure optimal shelf-life.

Description

View Zyphrine description for details of the chemical structure and excipients (inactive components).

Action

View Zyphrine mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antihistamines & Antiallergics

ATC Classification

R06AE09 - levocetirizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.

Regulatory Classification

Presentation/Packing

Form

Zyphrine syr 2.5 mg/5 mL

Packing/Price

60 mL x 1's (P197.96/bottle)

Zyphrine

levocetirizine

Manufacturer:

Stallion Labs

Distributor:

Cathay Drug