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Zimerz

Zimerz

memantine

Manufacturer:

Ildong Pharm

Distributor:

Patriot
Concise Prescribing Info
Contents
Memantine HCl
Indications/Uses
Alzheimer's disease (moderate to severe w/ or w/o dementia) & Parkinson's disease w/ dementia.
Dosage/Direction for Use
Initially 5 mg daily in the morning for the 1st wk, increased wkly at 5-mg increments to a max dose of 20 mg daily. Dose ≥10 mg should be taken in 2 divided doses.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Close monitoring in patients w/ recent MI, uncompensated CHF & uncontrolled HTN. Patients at risk of convulsions; conditions that increase urinary pH (eg, drastic changes in diet, renal tubular acidosis, severe UTI). Seizures may occur rarely. Renal impairment. Pregnancy & lactation. Childn.
Adverse Reactions
Constipation, dizziness, headache, somnolence. Anxiety, hallucinations, confusion, abnormal gait, hypertonia, vomiting, cystitis, increased libido.
Drug Interactions
May increase incidence & severity of adverse effects w/ amantadine, ketamine or dextromethorphan. Enhanced effects of dopaminergics & antimuscarinics. May reduce actions of barbiturates & antipsychotics. May alter effects of antispasmodics, baclofen & dantrolene. Reduced clearance w/ carbonic anhydrase inhibitors & Na bicarbonate.
MIMS Class
Neurodegenerative Disease Drugs / Antiparkinsonian Drugs
ATC Classification
N06DX01 - memantine ; Belongs to the class of other anti-dementia drugs.
Presentation/Packing
Form
Zimerz FC tab 10 mg
Packing/Price
100's (P4,217.85/pack)
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