Adults and children over 12 years of age: 1-2 g (potency) of Ceftriaxone sodium administered once daily intravenously or intramuscularly. In severe cases or in infections caused by moderately sensitive organisms, the dosage may be increased to 4 g (potency) once daily.
Neonates (within 14 days): A daily dose of 20-50 mg (potency)/kg of body weight, not to exceed 50 mg (potency)/kg. It is not necessary to differentiate between premature and infants born at full term.
Infants and children (15 days to twelve years): 20-80 mg/kg (potency) is administered once daily. For children with bodyweight of 50 kg or more, the usual adult dosage should be used intravenous doses of 50 mg (potency) or more per kg bodyweight should be given by infusion over at least 30 minutes.
Elderly patients: The dosage recommended for adults is applied to geriatric patients.
Meningitis: In bacterial meningitis in infants and children, treatment begins with doses of 100 mg (potency) per kg (not to exceed 4 g (potency)) once daily. As soon as the causative organism has been identified and its sensitivity determined, the dosage can be reduced accordingly.
The following duration of therapy has shown to be effective: (N. meningitidis: 4 days/H. influenzae: 6 days/S. pneumoniae: 7 days).
Gonorrhea: For the treatment of gonorrhea (penicillinase producing and nonpenicillinase-producing strains), a single IM dose of 250 mg (potency) is recommended.
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