Zemiglo Dosage/Direction for Use

Posology: Adults: The maximum daily recommended dose of Gemigliptin tablet is 50 mg once daily. If a dose is missed, it should be taken as soon as the patient remembers. A double dose should not be taken on the same day.
When used in combination with a sulfonylurea, a lower dose of the sulfonylurea may be required to reduce the risk of hypoglycaemia (see Precautions).
No dosage adjustment is required for patients with impaired renal function (see Precautions).
Additional information on special populations: Renal impairment: For patients with renal impairment, no dose adjustment is required.
Cardiac Impairment: There is limited clinical experience in patients with New York Heart Association (NYHA) Class I cardiac status. Therefore, gemigliptin should be used with caution in this population. Gemigliptin is not recommended in patients with NYHA Class II-IV cardiac status.
Hepatic Impairment: No dose adjustment is necessary for patients with mild or moderate hepatic impairment. There is no clinical experience in patients with severe hepatic impairment. Therefore, caution should be exercised in this population.
Elderly: The efficacy and safety of gemigliptin were not different between young and elderly patients. However, gemigliptin should be used with caution in elderly patient because physiological functions including liver and kidney are usually decreased in this population.
Pediatric Population: Safety and effectiveness in children and adolescents less than 18 years of age have not been established.
Method of Administration: Gemigliptin tablet 50 mg can be taken with or without food.