Xuvan/Xuvan XL Dosage/Direction for Use

Strict aseptic administration technique must be followed. Inject subcutaneous lidocaine or similar local anesthesia/anesthetic prior to injection of Xuvan/Xuvan XL.
Aspirate joint effusion before injection of Xuvan/Xuvan XL. Do not use the same syringe for removing joint effusion and for injection of Xuvan/Xuvan XL.
Take care to remove the tip cap of the syringe and needle aseptically. Inject Xuvan/Xuvan XL into the joint through a 19G sterile Needle/19 gauge needle.
The syringe is intended for single use. The contents of the PFS/syringe must be used immediately once the container is opened. Before injection, the air bubbles are removed from the injection.
Xuvan: Direction for Use: Xuvan is administered by intra articular injection. A treatment cycle consists of three to five injections given at weekly intervals. Several joints can be treated simultaneously.
Inject the full 2 mL in one knee only. If treatment is bilateral, a separate syringe should be used for each knee.
Xuvan XL: A single injection of Xuvan XL is administered by intra-articular route.
Inject the full 6 mL in one knee only. If treatment is bilateral, a separate syringe should be used for each knee.