Sign Out
Each tablet contains Irbesartan 150 mg.
Irbesartan is a potent, orally active, selective angiotensin II receptor (type AT1) antagonist. It is expected to block all actions of angiotensin II mediated by the AT1 receptor, regardless of the source or route of synthesis of angiotensin II. The selective antagonism of the angiotensin II (AT1) receptors results in increase in plasma renin levels and angiotensin II levels and a decrease in plasma aldosterone concentration. Serum potassium levels are not significantly affected by Irbesartan alone at the recommended doses. Irbesartan does not inhibit ACE (kininase II), an enzyme which generates angiotensin II and also degrades bradykinin into inactive metabolites. Irbesartan does not require metabolic activation for this activity.
Continue with Google