Verorab Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing Brand Resources

Concise Prescribing Info

Contents

Inactivated rabies vaccine produced in Vero cells

Indications/Uses

Pre- & post-exposure rabies prophylaxis in all age groups.

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Dosage/Direction for Use

Pre-exposure prophylaxis Immunocompetent individual Conventional regimen: 0.5 mL IM or 0.1 mL intradermal on day 0, 7, & 21 or 28. 1-week regimen: 0.5 mL IM on day 0 & 7; or 2 doses of 0.1 mL intradermal on day 0 & 7. Individual w/ decreased immunity Follow the conventional 3-dose regimen. Post-exposure prophylaxis Adjusted to exposure category, condition of animal, & vaccination status of the patient in accordance w/ official recommendations. Non-immunised individual & individual w/ decreased immunity IM 0.5 mL on day 0, 3, 7, 14 & 28; or 2 doses of 0.5 mL on day 0, followed by 0.5 mL on day 7 & 21. Intradermal 2 doses of 0.1 mL in 2 separate sites on day 0, 3, 7 & 28; or 2 doses of 0.1 mL in 2 separate sites on day 0, 3 & 7; or 4 doses of 0.1 mL in 4 separate sites on day 0, 3 & 7. Already immunised individual 1 dose (0.5 mL IM or 0.1 mL intradermal) on day 0 & 3. Alternatively, 4 intradermal inj of 0.1 mL in 4 separate sites on day 0.

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Contraindications

Pre-exposure: Hypersensitivity. Postpone vaccination in case of fever or acute disease.

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Special Precautions

Not to be administered via intravascular route & into the buttocks region. Individuals allergic to polymyxin B, streptomycin, neomycin (present in trace amounts in the vaccine) or to any antibiotic of the same class. Appropriate medical treatment & supervision must be readily available in case of rare anaphylactic reaction after administration. Perform serological tests in accordance w/ official recommendations. Perform blood test 2-4 wk after vaccination in subjects w/ immunodeficiency to ensure that protective immunising response was obtained. Risk of bleeding during IM administration in patients w/ thrombocytopenia or clotting disorders. Contains phenylalanine. Can temporarily affect ability to drive or use machines.

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Use In Pregnancy & Lactation

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Adverse Reactions

Generally feeling unwell, cephalalgia, myalgia, inj site pain, erythema or swelling; irritability, inconsolable crying & drowsiness in babies. Fever, lymphadenopathy, allergic reactions (eg, rash & itching), flu-like syndrome, inj site pruritus & induration; difficulty sleeping in babies.

Drug Interactions

Immunosuppressives, including long-term systemic corticosteroid therapy, may interfere w/ Ab production & lead to vaccination failure. Do not combine rabies Ig or any other product & rabies vaccine in the same syringe or inj into the same site.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Verorab detailed prescribing information

Storage

View Verorab storage conditions for details to ensure optimal shelf-life.

Description

View Verorab description for details of the chemical structure and excipients (inactive components).

Action

View Verorab mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Vaccines, Antisera & Immunologicals

ATC Classification

J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.

Regulatory Classification

Presentation/Packing

Form

Verorab powd for susp for inj 3.25 IU/0.5 mL

Packing/Price

(+ 0.5 mL solvent in pre-filled syringe) 1's

Verorab

rabies vaccine

Manufacturer:

Sanofi Pasteur

Distributor:

Zuellig