Veropres Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Norepinephrine

Indications/Uses

Secondary treatment of acute hypotension or shock according to different diseases (shock due to MI, & septicemia caused by shock, anaphylactic shock, hypotension or shock, according to the decreased circulating blood vol, acute hypotension during anesth) & cardiac arrest.

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Dosage/Direction for Use

Acute hypotension or shock Individualized dose. IV infusion at 2-3 mL/min. Maintenance: 0.5-1 mL/min. Cardiac arrest Inj IV in case of acute hypotension or shock after retaining valid heart rate & ventilation while cardiac resuscitation.

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Overdosage

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Contraindications

Patients w/ low BP due to lack of blood vol (except for emergency situations to maintain cerebral perfusion); high BP; hyperthyroidism; pheochromocytoma; pulmonary heart disease; severe arrhythmia; anesthetized fingers, toes, nose. Renal dysfunction. Pregnancy.

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Warnings

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Special Precautions

Hypersensitivity w/ Na sulfite. Patients w/ cocaine poisoning; ventricular tachycardia; atherosclerosis; heart disease; bradycardia; coronary, mesenteric, peripheral vascular thrombosis; hypotension due to MI; Prinzmetal angina. Do not use as substitute for blood or fluids. May cause an excessive increase in BP & acute pulmonary edema action, arrhythmia, cardiac arrest may occur. Frequently check BP & administration rate to avoid high increase in BP. May cause remarkable peripheral & internal vasoconstriction, decrease in renal perfusion & urea emission, decrease in blood vol despite normal BP, tissue hypoxia, metabolic acidosis w/ continuous use w/o replacement for maintaining of BP; consider using w/ blood vol replacement. Lactation. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Ischemic injury due to potent vasoconstrictor action & tissue hypoxia; cardiogenic shock, arrhythmia, bradycardia, stress cardiomyopathy; anxiety, transient headache; resp difficulty; extravasation necrosis at inj site.

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Drug Interactions

Increased risk of ventricular tachycardia or fibrillation w/ cyclopropane & halothane anesth. May cause severe, prolonged HTN w/ MAOIs or antidepressants of triptyline or imipramine types.

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Caution For Usage

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Storage

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Description

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Action

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MIMS Class

Vasoconstrictors

ATC Classification

C01CA03 - norepinephrine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.

Regulatory Classification

Presentation/Packing

Form

Veropres soln for inj 10 mg/10 mL

Packing/Price

10 mL x 10 × 1's

Form

Veropres soln for inj 4 mg/4mL

Packing/Price

4 mL x 10 × 1's

Veropres

norepinephrine

Manufacturer:

BCWorld Pharm

Distributor:

Cathay Drug