Veral Dosage/Direction for Use

Verapamil hydrochloride is to be dosed on an individual basis, adapted to the severity of the disease. According to long-standing clinical experience, the mean dose is between 240 and 360 mg per day in almost all indications.
A daily dose of 480 mg should not be exceeded as long-term therapy, short term increase is possible.
As far as not otherwise prescribed, the following dose guidelines apply: See Table 1.

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Children and adolescents: The safety and efficacy of verapamil prolonged release tablets in children and adolescents have not been established. No data are available.
Impaired renal function: Currently available data are described in Precautions. Verapamil hydrochloride should be used cautiously and with close monitoring in patients with impaired renal function.
Impaired hepatic function: Depending on the severity of the disease in patients with impaired hepatic function, the effect of verapamil hydrochloride is increased and prolonged, due to a decelerated degradation of the medicinal product. For this reason, the dose should be adjusted with special care in these cases and be started with low doses (e.g. in patients with hepatic dysfunction, first 40 mg verapamil hydrochloride 2-3 times daily, equivalent to 80-120 mg verapamil hydrochloride per day).
Method of duration of administration: The tablets are to be taken without sucking and chewing together with a sufficient quantity of liquid (e.g. a glass of water, no grapefruit juice) preferably with or shortly after meals.
Do not take Verapamil hydrochloride in lying position.
Verapamil hydrochloride must not be used in patients with angina pectoris after myocardial infarction until 7 days after the acute infarction.
The duration of treatment is not limited.
After longer-term treatment, Verapamil hydrochloride should generally not be discontinued abruptly, but gradually.