Venacure

Each film-coated tablet contains: 500 mg micronized purified flavonoid fraction of rutaceae equivalent to Diosmin 450 mg, Hesperidin 50 mg.

This medicine contains Diosmin + Hesperidin and is a phlebotonic and a vascular-protecting agent.
The efficacy of Diosmin + Hesperidin is accounted for by its specific action on the principal elements of venous disease.
Diosmin + Hesperidin is phlebotonic: It reinforces venous tone by prolonging the activity of parietal noradrenaline. Thus, Diosmin + Hesperidin decreases venous capacitance, venous distensibility and venous emptying time. Diosmin + Hesperidin protects the microcirculation by fighting the microcirculation-damaging process; it combats venous inflammation by decreasing leukocyte activation and as a consequence, by inhibiting the release of inflammatory mediators, principally free radicals and prostaglandins. Thus, Diosmin + Hesperidin normalizes capillary permeability and strengthens capillary resistance.
Diosmin + Hesperidin acts on the lymphatic system: It improves lymphatic drainage by increasing lymph flow and lymph oncotic pressure. This action on the lymphatic system associated with a phlebotonic and vasculoprotective effect, explains the activity of Diosmin + Hesperidin on CVD-associated edema.
Diosmin + Hesperidin is highly effective in the treatment of chronic hemorrhoids disease. It significantly improves subjective symptoms and objective signs e.g., anal discomfort, pain, redness, anal discharge, proctitis, tenesmus, pruritus, erythema and bleeding. Diosmin + Hesperidin also significantly reduces the frequency, severity and duration of acute hemorrhoidal attacks and bleeding by chronic treatment.

This medicine is used for the treatment of the symptoms and signs of organic and idiopathic chronic venous disease of the lower limbs e.g., heavy legs, pain, heat sensation, edema, functional impairment and nocturnal cramps. Treatment of the symptoms of acute hemorrhoidal attacks and chronic hemorrhoidal treatment.

Always take Diosmin + Hesperidin exactly as the doctor or health care provider has told the patient.
Dosage: Usual Dose: Chronic Venous Disease: 2 tablets daily with meals.
Chronic Hemorrhoidal Disease: 2 tablets daily with meals.
Acute Hemorrhoidal Attack: 6 tablets daily (in 2 divided doses) for 4 days, then 4 tablets daily (in 2 divided doses) for 3 days, 2 tablets thereafter.
Should be taken with food: Take at mealtime.
If The Patient Misses a Dose: Take the missed dose as soon as the patient remembers. If it is almost time for the next dose, skip the missed dose and return to the normal dosing schedule.
Do not double a dose under any circumstances.
If the patient often forgets to take the medicines, let the doctor and pharmacist know.

Signs and Symptoms of Overdose: The most frequently reported adverse events in overdose cases were gastrointestinal events (such as diarrhea, nausea, abdominal pain) and skin events (such as pruritus, rash).
If The Patient Has Taken More Than the Recommended Dosage: If the patient has taken more than the recommended dosage of this medicine and is experiencing adverse symptoms, seek medical attention immediately.

Do not take this medicine if the patient is hypersensitive to the active substance or to any of the excipients of Diosmin + Hesperidin.

When to Consult the Doctor: If patient is experiencing an adverse reaction to this medicine, it would be best to consult the doctor as soon as possible.

Let the doctor know if the patient is pregnant and breastfeeding.

Diosmin + Hesperidin may cause any of the following side effects: headache, dizziness, diarrhea, indigestion, stomach pain, nausea, vomiting, constipation and skin itching.
If the patient develops rashes, breathlessness, swollen mouth, lips, tongue or eyes, stop taking this medicine and inform a doctor immediately. These could be sign of an allergic reaction.

Inform the doctor and pharmacist if the patient is taking any of these medicines: diclofenac (NSAID or medicine for pain and inflammation), chlorzoxazone (medicines used for muscle spasm pain), fexofenadine (medicines for cold and allergy).
This list does not include all medicines that may interact with Diosmin + Hesperidin.
Always notify the doctor and pharmacist if the patient is taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that the patient buys without a prescription.

Store at temperatures not exceeding 30°C.

Anorectal Preparations / Phlebitis & Varicose Preparations

C05CA53 - diosmin, combinations ; Belongs to the class of bioflavonoids used as capillary stabilizing agents.

Non-Rx