Vaneular Overdosage

Vitamin B₆: Although vitamin B₆ has generally been considered relatively nontoxic, long term (two months or longer) administration of large (megadose) dosages (usually 2 grams or more daily) of vitamin B₆ can cause neurological symptoms manifested as paresthesia (more noticeable at night and limited to the extremities), bone pains (described as lightning, stabbing or shooting like a knitting needle or electric shocks), hyperesthesia (described as burning, pricking, stinging, or itching), muscle weakness (difficulty in running, lifting, climbing stairs and loss of manual dexterity), fasciculation (described as twitching, restlessness or fidgeting), and numbness of the limbs and face.
Nicotinic Acid: High-doses of Nicotinic Acid equivalent to 1.5 grams daily may cause dizziness, palpitations, shortness of breath, sweating, insomnia, nausea, vomiting, abdominal pain, and myalgia (muscle pain).
If the patient has taken more than the recommended dosage, consult a doctor or contact a Poison Control Center right away.