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Valpros i-IV: Preparation of Intravenous Injection/Infusion: To reconstitute, inject the solvent provided (4 mL) into the vial, allow to dissolve and extract the appropriate dose. Due to displacement of solvent by the sodium valproate, the concentration of the reconstituted preparation is 95 mg/mL. The reconstituted vial is stable for 8 hours at 25°C and for 24 hours at 5°C.
Compatibility and Stability: Sodium valproate powder for injection, once reconstituted and diluted in 500 mL of the IV solution (0.9% sodium chloride, 5% glucose and Lactated Ringer's solution), is stable for 6 hours at 25°C and for 24 hours when kept at 5°C.
Prior to administration, parenteral products should be inspected visually for particulate matter and discoloration.
Shake the reconstituted solution before use.
Observe strict aseptic technique when drawing up the contents of the vial. If contaminated, it has the potential to become a source of infection to patients.
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