Pharmacologic Classification: Analgesic/Decongestant/Antitussive.
Pharmacology: Dextromethorphan Hydrobromide: acts centrally to elevate the threshold for coughing. It has no analgesic or additive properties. The onset of antitussive action occurs in 15 to 30 minutes after administration and is of long duration.
Paracetamol: the analgesic action of Paracetamol involves peripheral and central influence, but the specific mechanism is as yet undetermined. Antipyretic activity is mediated through hypothalamic heat regulating centers. Paracetamol inhibits prostaglandin synthetase. Therapeutic doses of Paracetamol have negligible effects on the cardiovascular or respiratory systems; however, toxic doses may cause circulatory failure and rapid, shallow breathing.
Phenylephrine Hydrochloride: is a sympathomimetic which acts predominantly on alpha receptors and has little action on beta receptors. It therefore functions as an oral nasal decongestant with minimal Central nervous system (CNS) stimulation.
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