When used as monotherapy, the dose is one drop of DORZOLAMIDE HCl (TRUSOPT) Ophthalmic Solution in the affected eye(s) three times daily. 
When used as adjunctive therapy with an ophthalmic beta-blocker, the dose is one drop of DORZOLAMIDE HCl (TRUSOPT) in the affected eye(s) two times daily. 
When substituting DORZOLAMIDE HCl (TRUSOPT) for another ophthalmic antiglaucoma agent, discontinue the other agent after proper dosing on one day, and start DORZOLAMIDE HCl (TRUSOPT) on the next day. 
If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.
                                
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