Trulicity Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Dulaglutide

Indications/Uses

Adults w/ insufficiently controlled type 2 DM as an adjunct to diet & exercise: As monotherapy when metformin is considered inappropriate due to intolerance or contraindications; or in addition to other medicinal products for the treatment of diabetes.

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Dosage/Direction for Use

SC (abdomen, thigh or upper arm) Monotherapy 0.75 mg once wkly. Add-on therapy 1.5 mg once wkly. Potentially vulnerable population Starting dose: 0.75 mg once wkly.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity.

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Special Precautions

Not to be administered IV or IM. Not to be used in patients w/ type 1 DM or for the treatment of diabetic ketoacidosis. Not a substitute for insulin. Potential risk of dehydration, particularly in relation to GI adverse reactions; avoid fluid depletion. Not recommended in patients w/ severe GI disease, including severe gastroparesis; ESRD (<15 mL/min/1.73 m²). Discontinue if acute pancreatitis is suspected. Increased risk of hypoglycemia in combination w/ sulphonylurea or insulin. Advise patients to take precautions avoiding hypoglycemia while driving & using machines. Not recommended during pregnancy. Not to be used during lactation. Safety & efficacy in childn <18 yr have not yet been established.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypoglycaemia; nausea, diarrhoea, vomiting, abdominal pain. Decreased appetite, dyspepsia, constipation, flatulence, abdominal distention, GERD, eructation; fatigue; sinus tachycardia, 1st degree AV block.

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Drug Interactions

Delayed gastric emptying & has potential to impact rate of absorption of oral medicinal products. Potential for altered exposure to patients in combination w/ oral medicinal products w/ rapid GI absorption or PR formulation. Increased exposure w/ sitagliptin may enhance effects on blood glucose levels.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Trulicity detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BJ05 - dulaglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Trulicity soln for inj 0.75 mg

Packing/Price

0.5 mL x 4 × 1's

Form

Trulicity soln for inj 1.5 mg

Packing/Price

0.5 mL x 4 × 1's

Trulicity

dulaglutide

Manufacturer:

Eli Lilly

Distributor:

Zuellig