Posology: Fluticasone furoate + Umeclidinium + Vilanterol (Trelegy Ellipta) is for oral inhalation only. 
After inhalation, the patient should rinse their mouth with water without swallowing.
Populations: Adults: The recommended and maximum dose is one inhalation of Fluticasone furoate + Umeclidinium + Vilanterol (Trelegy Ellipta) 100/62.5/25 micrograms once daily, at the same time each day.
Children and adolescents: Use in patients less than 18 years of age is not relevant given the indication for this product.
Elderly: No dosage adjustment is required in patients over 65 years (see Pharmacology: Pharmacokinetics: Special Patient Populations under Actions). 
Renal impairment: No dosage adjustment is required for patients with renal impairment (see Pharmacology: Pharmacokinetics: Special Patient Populations under Actions). 
Hepatic Impairment: No dosage adjustment is required in patients with hepatic impairment. Umeclidinium has not been studied in patients with severe hepatic impairment (see Precautions and Pharmacology: Pharmacokinetics: Special Patient Populations under Actions).
                                
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