Torfil 2.5/Torfil 10/Torfil 20 Dosage/Direction for Use

Torfil 2.5: Tablet should be swallowed whole and without regards to food. The recommended dose is 5 mg taken one tablet per day at the same time every day without regard to timing of sexual activity for the treatment of Erectile dysfunction and benign prostatic hyperplasia. When therapy for BPH is initiated with finasteride, the recommended dose is 5 mg once daily for 26 weeks.
Renal impairment: Tadalafil is not recommended for daily use in treatment of erectile dysfunction and benign prostatic hyperplasia with patients in which creatinine clearance is less than 30mL/min. or on hemodialysis. As for patients with creatinine clearance of less than 30mL/min. to 50mL/min, the recommended dose for treatment of benign prostatic hyperplasia and erectile dysfunction is 5 mg based on the individual's response.
Hepatic Impairment: There is no established study regarding the use of tadalafil in patients with mild to moderate hepatic impairment (Child Pugh Class A or B). Therefore, caution is advised if daily use is prescribed to these patients. The use of tadalafil in patients with severe hepatic impairment (Child Pugh Class C) is not recommended.
Elderly: No dosage adjustment required.
Children: Tadalafil is not recommended for use in individuals below 18 years of age.
Torfil 10/Torfil 20: The recommended dose of Tadalafil is 20 mg, taken prior to anticipated sexual activity and without regard to food. It can be taken up to 36 hours and as early as 30 minutes prior to sexual activity. Patients may engage in sexual activity at different time points to determine their own optimal window of responsiveness. The maximum dosing frequency is one tablet per day taken without regards to food.
Elderly Men: Dose adjustments are not required in elderly patients.
Renal Impairment: Dose adjustments are not required in patients with mild to moderate renal impairment.
Hepatic Impairment: Dose adjustments are not required in patients with hepatic impairment. However, caution is advised when Tadalafil is used in patients with severe hepatic impairment (Child-Pugh Class C).
Diabetes: Dose adjustments are not required in diabetic patients.
Children: Tadalafil is not recommended for use in individuals below 18 years of age.