Tolnaftate: Uses, Dosage, Side Effects and More

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Philippines prescribing information.

Generic Medicine Info

Indications and Dosage

Topical/Cutaneous
Superficial dermatophyte infections

Adult: As 1% gel/soln/powd/cream: Apply a thin layer to the affected area(s) bid. As powder/liq spray: Spray a thin layer to the affected area(s) bid. Treatment duration: 2 wk (tinea cruris); 4 wk (tinea corporis, tinea pedis).
Child: ≥2 yr Same as adult dose.

What are the brands available for Tolnaftate in Philippines?

Contraindications

Hypersensitivity.

Special Precautions

Not intended for use for nail or scalp infections.

Adverse Reactions

Dermatologic: Irritation, contact dermatitis, pruritus, stinging.

Patient Counseling Information

Avoid contact w/ eyes.

Action

Description:
Mechanism of Action: Tolnaftate is a synthetic thiocarbamate antifungal agent which inhibits the growth of dermatophytes (e.g. Epidermophyton, Micosporum, Trichophyton spp., Malassezia furfur) by distorting the hyphae and stopping mycelial growth in susceptible fungi. It is inactive against Candida spp. or bacteria.
Onset: 24-72 hr.

Chemical Structure

Storage

Store between 20-25°C.

MIMS Class

Topical Antifungals & Antiparasites

ATC Classification

D01AE18 - tolnaftate ; Belongs to the class of other antifungals for topical use.

References

Anon. Tolnaftate. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 23/10/2017.

Buckingham R (ed). Tolnaftate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 23/10/2017.

McEvoy GK, Snow EK, Miller J et al (eds). Tolnaftate (Topical). AHFS Drug Information (AHFS DI) [online]. American Society of Health-System Pharmacists (ASHP). https://www.medicinescomplete.com. Accessed 23/10/2017.

Tinactin Cream (Bayer Healthcare LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 26/10/2017.

Tolnaftate Gel (Alva-Amco Pharmacal Companies, Inc.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 26/10/2017.

Tolnaftate Liquid Spray (Topco Associates LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 26/10/2017.

Tolnaftate Powder Spray (CVS Pharmacy). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 26/10/2017.

Tolnaftate Solution (Perrigo New York Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 26/10/2017.

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