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Bleeding Risk: Ticalor, like the other antiplatelet agents, can cause significant, sometimes fatal bleeding (see Precautions and Adverse Reactions).
Do not use Ticalor in patients with active pathological bleeding or a history of intracranial haemorrhage (see Contraindications).
Do not start Ticalor in patients undergoing urgent coronary artery bypass graft surgery (CABG).
If possible, manage bleeding without discontinuing Ticalor. Stopping Ticalor increases the risk of subsequent cardiovascular events.
Aspirin dose and Ticalor effectiveness: Maintenance doses of aspirin above 100 mg reduce the effectiveness of Ticalor and should be avoided.
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