Thyroxil Adverse Reactions

The following effects are indicative of excessive dosage and usually disappear on reduction of dosage or withdrawal of treatment for a few days. The frequency classification for these adverse reactions is not known due to a lack of robust clinical trial data to accurately determine frequency estimates.
Immune system disorders: Hypersensitivity reactions such as skin rash and pruritus.
Metabolism and nutrition disorders: Increased appetite, abnormal loss of weight.
Endocrine disorders: Hyperthyroidism.
Gastrointestinal disorders: Abdominal cramps, nausea, vomiting, diarrhea.
Nervous system disorders: Headache, tremors, seizure. Rare cases of pseudotumor cerebri (benign intracranial hypertension) have been reported especially in children.
Cardiac disorders: Anginal pain, cardiac arrhythmias, palpitations, tachycardia, increased blood pressure, heart failure, myocardial infarction.
Respiratory, thoracic and mediastinal disorders: Dyspnea.
Skin and subcutaneous tissue disorders: Sweating, alopecia.
Vascular disorders: Flushing.
Musculoskeletal and connective tissue disorders: Cramps in the skeletal muscle, muscular weakness. Excessive dose may result in premature closure of epiphyses in children with compromised adult height.
Congenital, familial and genetic disorders: Excessive dose may result in craniosynostosis in infants.
Psychiatric disorders: Anxiety, emotional lability, nervousness, excitability, insomnia, restlessness.
Reproductive system and breast disorders: Menstrual irregularity, impaired fertility.
General disorders and administration site conditions: Fatigue, heat intolerance, fever.