Thydin Dosage/Direction for Use

Levothyroxine Sodium Tablet (Thydin) is taken orally as a single daily dose, preferably one-half to one hour before breakfast. It should be taken at least 4 hours apart from drugs that are known to interfere with its absorption. Replacement dose should not be administered in a large volume of water for infants being breastfed. A tablet may be crushed in small amount of water to give a paste which may be given to an infant for sucking.
Adults: For adults with hypothyroidism, the initial daily dose is 50 mcg to 100 mcg increased by increments of 25 mcg to 50 mcg every 14 days to achieve a euthyroid state. Maintenance dose is usually 100 mcg to 200 mcg daily.
For adults who had undergone radiological or surgical treatment, rapid replacement therapy must be achieved.
To suppress Thyroid Stimulating Hormone (TSH) in adults, daily dose of 2.6 mcg per kilogram body weight is given.
Elderly: For elderly patients with cardiovascular disorder, initial dose is 12.5 mcg daily increased by increments of 12.5 mcg to 25 mcg every four weeks.
For patients over 60 years of age, the maintenance dose is about 25 percent lower than in younger adults.
Children: For neonates, the treatment is given in full replacement dose for rapid replacement. Treatment in children over 1 year old starts with 2.5 mcg to 5 mcg per kg body weight daily. The dose is gradually increased to achieve a euthyroid state.
For children less than 6 months old, 8 mcg to 10 mcg per kilogram body weight is usually given with daily replacement dose of 25 mcg to 50 mcg.
For 6 to 12 months old, 6 mcg to 8 mcg per kilogram body weight is given usually comprising of about 50 mcg to 75 mcg daily.
For children 1 to 5 years of age, about 75 mcg to 100 mcg daily replacement dose is given calculated at 5 mcg to 6 mcg per kilogram body weight.
For children 6 to 12 years of age, about 100 mcg to 150 mcg daily replacement dose is given calculated at 4 mcg to 5 mcg per kilogram body weight.
For children over 12 years of age, 2 mcg to 3 mcg per kilogram body weight is given with usual dose of 100 mcg to 200 mcg daily.
Or as prescribed by the physician.