TGP Levothyroxine Sodium Dosage/Direction for Use

In hypothyroidism an initial adult dose of 50 to 100 mcg daily by mouth may be increased by 25 to 50 mcg at intervals of about 4 weeks until the thyroid deficiency is corrected ad maintenance dose is established.
The adult maintenance dose is usually between 100 and 200 mcg daily. In elderly patients, in those with cardiovascular disorder, or in those with severe hypothyroidism of long standing, the treatment should be introduces more gradually: an initial dose of 12.5 to 50 mcg daily increased by increments of 12.5 to 25 mcg at intervals of about 4 weeks maybe appropriate.
In children, individualization of dosage and monitoring of treatment is especially important. One recommended regimen for the treatment of congenital hypothyroidism is 10 to 15 micrograms per kg body-weight daily, adjusted as necessary. Another regimen suggests an initial dose of 5 to 10 micrograms per kg daily in children up to 1 month of age (or 5 micrograms per kg in children over 1 month), adjusted in steps of 25 micrograms every 2 to 4 weeks until mild toxic symptoms appear, at which time the dosage is slightly reduced. For juvenile myxedema, children over 1 year of age may be given 2.5 to 5 micrograms per kg body-weight daily initially.