Tetralysal Special Precautions

Solid dosage forms of tetracyclines may cause oesophageal irritation and ulceration. To avoid oesophageal irritation and ulceration, adequate fluids (water) should be taken with this medicinal product (see DOSAGE & ADMINISTRATION).
Caution should be exercised if the product is administered to patients with impaired renal or hepatic functions.
Overdosage of tetracyclines could result in hepatotoxicity.
High dosage of tetracyclines may be nephrotoxic.
Due to the risks of photosensitivity, it is recommended to avoid exposure to direct sunlight and ultraviolet light during treatment which should be discontinued if erythematous cutaneous manifestations occur.
The use of expired tetracyclines can lead to renal tubular acidosis (Pseudo-Fanconi syndrome) readily reversible when treatment is discontinued.
Treatment with Lymecycline (Tetralysal) should be discontinued if any evidence of raised intracranial pressure develops during treatment.
Prolonged use of broad-spectrum antibiotics may result in the appearance of resistant organisms and superinfection.
Tetracyclines in general can cause exacerbation of systemic lupus erythematosus.
Caution should be observed in the treatment of patients with myasthenia gravis who may be at risk of worsening of the condition.
Effects on the Ability to Drive and Use Machines: Not applicable.