Postexposure Prophylaxis: Immediate prophylaxis after tetanus prone injuries in patients not adequately vaccinated, whose immunisation status is not known with certainty, with severe deficiency in antibody production.
Therapy of Clinically Manifest Tetanus: Tetanus immunoglobulin should always be administered in conjunction with an active tetanus vaccination unless there are contraindications or confirmation of adequate vaccination.
WHO guidelines and other official guidance regarding the use of human tetanus immunoglobulin for intramuscular use should be observed.
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