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Pharmacologic Classification: Antifibrinolytic.
Pharmacology: Pharmacokinetics: Absorption: Absorbed from the gastrointestinal tract. Bioavailability: Approximately 45% (oral). Time to peak plasma concentration: 2.5 hours after oral administration (range: 1-5 hours).
Distribution: Widely distributed throughout the body. It crosses the placenta and enters breast milk. Volume of distribution: 9-12 L. Plasma protein-binding: Approximately 3%, mainly to plasminogen.
Excretion: Via urine (>95%, as unchanged drug). Elimination half-life: Approximately 2-11 hours.
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