Tapdin Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Methimazole (thiamazole)

Indications/Uses

Management of hyperthyroidism including treatment of Grave's disease; prep of hyperthyroid patients for thyroidectomy. Adjunct to radio-iodine therapy & treatment of thyroid storm.

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Dosage/Direction for Use

Adult Initially 15-60 mg daily in single or divided doses. Euthyroid patient 5-15 mg daily. Maintenance: 5-15 mg daily. Childn Initially 400 mcg/kg daily. Maintenance: ½ of initial dose.

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Overdosage

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Administration

Should be taken with food.

Contraindications

Hypersensitivity. Nursing mothers.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Tapdin detailed prescribing information

Special Precautions

Patients should undergo close surveillance & monitored for mouth ulcers, sore throat, fever, bruising & malaise. May cause fetal harm when administered in the 1st trimester of pregnancy. Should not be given during pregnancy & lactation. Scalp defects, choanal, esophageal atresia & tracheoesophageal fistula in exposed infants. Monitor neonatal development & thyroid function closely in infants.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nausea & vomiting, gastric discomfort, skin rashes, pruritus, hair loss, headache, aplastic anemia or isolated thrombocytopenia & agranulocytosis, taste disturbance, arthralgia, myopathy, vasculitis, nephritis, lupus-like syndrome, neutropenia, liver damage.

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Drug Interactions

May potentiate activity of anticoagulants. Increased clearance of β blockers. Increased serum levels or digitalis glycosides. Decrease theophylline clearance.

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Storage

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Description

View Tapdin description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antithyroid Agents

ATC Classification

H03BB02 - thiamazole ; Belongs to the class of sulfur-containing imidazole derivative agents. Used in the management of thyroid diseases.

Regulatory Classification

Presentation/Packing

Form

Tapdin tab 20 mg

Packing/Price

100's (P2,750/box, P27.5/tab)

Form

Tapdin tab 5 mg

Packing/Price

100's (P725/box, P7.25/tab)

Tapdin

thiamazole

Manufacturer:

MedChoice Endocrine Group

Distributor:

MedChoice Endocrine Group