Prolonged use of topical corticosteroids may produce atrophy of the skin. Glucocorticoids may mask some signs of infection, and new infections may appear during their use.
Prolonged treatment may result in overgrowth of non-susceptible organisms and fungi.
Since systemic activity has not been seen with therapeutic doses of Synalar Otic Solution, care must be taken when transferring patients from systemic steroid therapy to Synalar Otic Solution if there is reason to suspect that their adrenal function is impaired.
Allergic cross-reactions may occur which could prevent future use of kanamycin, paromomycin and streptomycin.
Use in Pregnancy: See Use in Pregnancy & Lactation section for further information.
Use in Children: Administration of topical corticosteroids to children should be limited to a short time period and to the smallest amount of the product compatible with an effective therapeutic regimen.
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