Sybron

Each 5 mL syrup contains: Ambroxol Hydrochloride 15 mg.
Each mL oral drops contains: Ambroxol Hydrochloride 6 mg.
Ambroxol Hydrochloride is a derivative of the mucolytic, Bromhexine, which has been found to posses secretolytic and mucokinetic properties. It acts by increasing the production of serum concentrations of the bronchial mucus-secreting glands in the respiratory tract. Through its pulmonary surfactant stimulating activity, Ambroxol Hydrochloride accelerates mucus transport, promoting expulsion of thick, tenacious secretions from the respiratory tract.
During treatment with Ambroxol Hydrochloride, chronically inflamed bronchial mucosa tend to return to normal. The patients cough and sputum volumes is reduced; expectoration is facilitated; and breathing is eased considerably.
The good tolerability of Ambroxol Hydrochloride permits its long-term use.

For treatment of acute and chronic diseases of the respiratory tract associated with abnormal bronchial secretions, particularly in exacerbations of chronic bronchitis, asthmatic bronchitis, and bronchial asthma.

Syrup: Daily dose of 60 to 120 mg in 2 to 3 divided doses by mouth or as prescribed by the physician.
Adult and Children over 10 years: 10 mL (2 teaspoonfuls) three times a day.
Children below 10 years: 6-10 years old: 5 mL (1 teaspoonful) three times a day;
2-5 years old: 2.5 mL (½ teaspoon) three times a day.
Or as prescribed by the physician.
Oral drops: Infant ≤1 yr: 0.5-1.25 mL three times a day. Or as prescribed by the physician.

Patient who has hypersensitivity to this drug or its components.

Should be used with care in patients with a history of peptic ulceration.

Ambroxol Hydrochloride is generally well tolerated. Occasional incidence of headache, polyuria, and fatigue has been reported. Also mild gastrointestinal disturbances such as nausea, vomiting, and diarrhea may occur.
Gastrointestinal: Occasionally mild upper gastrointestinal adverse events including dyspepsia, nausea, vomiting, heartburn, and dry mouth may occur. Rarely stomach upset, abdominal fullness, abdominal pain, diarrhea, constipation, anorexia, etc. may occur.
Hypersensitivity: Allergic reactions have been rarely reported such as skin rash and severe acute anaphylactoid reaction (including anaphylactic shock). Urticaria, urticarial erythema, itching, vascular edema, face swelling, dyspnea, chills, etc. may occur.
Respiratory: Suppurative rhinitis with leukocytosis may occur.
Neural: Occasionally paresthesia of the tongue and taste changes have been reported. Rarely oral paralysis and paralysis of arm may occur.

No report of drug interaction. Ambroxol Hydrochloride can be administered with other drugs, particularly the standard medication for bronchitis syndrome such as corticosteroids, bronchospasmolytics, diuretics, and antibiotics.

Store at temperatures not exceeding 30°C.

Cough & Cold Preparations

R05CB06 - ambroxol ; Belongs to the class of mucolytics. Used in the treatment of wet cough.

Rx