Sultacillin Adverse Reactions

As with other parenteral antibiotics, the principal side effect observed is injection site pain, especially associated with the intramuscular route of administration. A small number of patients may develop phlebitis or an injection-site reaction after intravenous administration.
Body as a Whole: anaphylactoid reaction and anaphylactic shock.
Central and Peripheral Nervous: rare reports of convulsions.
Gastrointestinal: nausea, vomiting, diarrhea and pseudomembranous colitis.
Hematopoietic and Lymphatic: anemia, hemolytic anemia, thrombocytopenia and leukopenia have been reported during therapy with ampicillin sodium/sulbactam sodium. These reactions are reversible on discontinuation of therapy and are believed to be sensitivity reactions.
Liver/Biliary: transient elevations of ALT (SGPT) and AST (SGOT) transaminases, bilirubinemia, abnormal hepatic function and jaundice.
Skin/skin structure: rash, itching, other skin reactions, rare reports of Stevens Johnson syndrome, epidermal necrolysis and erythema multiforme.
Urinary: rare reports of interstitial nephritis.
Adverse reactions associated with the use of ampicillin alone may be observed with Ampicillin sodium/Sulbactam sodium IM/IV.