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Patients should be given a standard cholesterol-lowering diet prior to the start of treatment and maintained throughout the course of treatment.
Oral administration. The usual starting dose is 5 mg (one tablet), once a day. The choice of the starting dose should take into account the individual's cholesterol level, expected cardiovascular risk, and potential risk of adverse reactions. For patients who require a more
aggressive reduction of low-density lipoprotein cholesterol (LDL-C), a starting dose of 10 mg once a day should be considered, which controls lipid levels in most patients. If necessary, the dose can be adjusted to the higher dose level after 4 weeks of treatment. The maximum daily dose is 20 mg. Rosuvastatin can be administered as a single dose at any time of day, with or without food.
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