Stavance Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage Patient Counseling Information MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Vancomycin HCl

Indications/Uses

Serious or severe infections caused by susceptible strains of methicillin-resistant (β-lactam-resistant) staphylococci. Penicillin-allergic patients, for patients who cannot receive or who have failed to respond to other drugs, including penicillins or cephalosporins & for infections caused by vancomycin-susceptible organisms that are resistant to other antimicrobial drugs. Initial therapy when methicillin resistant staphylococci are suspected. Staphylococcal endocarditis. Alone or in combination w/ aminoglycoside for endocarditis caused by S. viridans or S. bovis; endocarditis caused by E. faecalis in combination w/ aminoglycoside. Diphtheroid endocarditis. Treatment or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. Antibiotic-associated Pseudomembranous colitis produced by C. difficile & for Staphylococcal enterocolitis.

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Dosage/Direction for Use

IV Adult 2 g divided either as 500 mg every 6 hr or 1 g every 12 hr administered at no ≥10 mg/min or at least 60 min. Childn 10 mg/kg/dose every 6 hr administered over at least 60 min. Neonate up to 1 mth Initially 15 mg/kg followed by 10 mg/kg every 12 hr in the 1st wk of life & every 8 hr thereafter up to 1 mth administered over 60 min. Mild or moderate renal insufficiency Initially 15 mg/kg.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Exaggerated hypotension, including shock when administered via rapid bolus. Should be diluted over a period of not <60 min to avoid rapid-infusion-related reactions. Transient or permanent ototoxicity. Adjust dosage in patients w/ renal dysfunction. C. difficile associated diarrhea. Pseudomembranous colitis due to C. difficile. Monitor renal function; leucocyte count. Extravasation; thrombophlebitis. Infusion-related events (including hypotension, flushing, erythema, urticaria & pruritus). Chemical peritonitis in IP route.

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Use In Pregnancy & Lactation

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Adverse Reactions

Rapid infusion: Anaphylactoid reactions, including hypotension, wheezing, dyspnea, urticaria, or pruritus; flushing of the upper body (''red neck'') or pain & muscle spasm of the chest & back. Increased serum creatinine or BUN conc. Pseudomembranous colitis. Ototoxicity. Neutropenia. Inflammation at the inj site. Anaphylaxis, drug fever, nausea, chills, eosinophilia, rashes including exfoliative dermatitis, linear IgA bullous dermatosis, SJS, TENS & vasculitis.

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Drug Interactions

Erythema & histamine-like flushing & anaphylactoid reactions w/ anesth. Potential neurotoxicity &/or nephrotoxicity w/ amphotericin B, aminoglycosides, bacitracin, polymyxin B, colistin, viomycin, or cisplatin.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Stavance detailed prescribing information

Storage

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Description

View Stavance description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Other Antibiotics

ATC Classification

J01XA01 - vancomycin ; Belongs to the class of glycopeptide antibacterials. Used in the systemic treatment of infections.

Regulatory Classification

Patient Counseling Information

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Presentation/Packing

Form

Stavance lyo powd for IV infusion 1 g

Packing/Price

1's

Form

Stavance lyo powd for IV infusion 500 mg

Packing/Price

1's

Stavance

vancomycin

Manufacturer:

Aspiro Pharma

Distributor:

Camber