Solitor 5 Dosage/Direction for Use

Posology: Adults, including the elderly: The recommended dose is 5 mg once daily. If needed, the dose may be increased to 10 mg once daily.
Pediatric population: The safety and efficacy of solifenacin in children have not yet been established. Therefore, Solifenacin should not be used in children.
Patients with renal impairment: No dose adjustment is necessary for patients with mild to moderate renal impairment (creatinine clearance >30 mL/min). Patients with severe renal impairment (creatinine clearance ≤30 mL/min) should be treated with caution and receive no more than 5 mg once daily.
Patients with hepatic impairment: Solifenacin is not recommended in patients with severe hepatic impairment. No dose adjustment is necessary for patients with mild hepatic impairment. Patients with moderate hepatic impairment (Child Pugh score of 7 to 9) should be treated with caution and receive no more than 5 mg once daily.
Potent inhibitors of cytochrome P450 3A4: The maximum dose of solifenacin should be limited to 5 mg when treated simultaneously with ketoconazole or therapeutic doses of other potent CYP3A4 inhibitors e.g. ritonavir, nelfinavir, itraconazole.
Method of administration: Solifenacin should be taken orally and should be swallowed whole with liquids. It can be taken with or without food.