Patients w/ recent heart attack, stroke, severe heart rhythm problems or chest pain; any heart problems; kidney or liver disease; stomach/duodenal ulcers or an inflamed oesophagus/gullet; seizures; overactive thyroid gland; high BP, angina or circulatory problems; pheochromocytoma; mouth inflammation or sore throat. Not recommended for patients who have found other forms of nicotine replacement therapy unsatisfactory. Reduce or discontinue use in case of an increase in heart problems. Monitor blood sugar levels more often than usual if patient has diabetes; insulin or medication requirements may change. Effect of some medicines can be altered when patient stops smoking. Pregnancy & lactation. Patients <18 yr.