Sergivell Plain: Bupivacaine Hydrochloride (Sergivell Plain) 5 mg/mL solution for injection is indicated in adults and children of all ages for intrathecal (subarachnoid) spinal anaesthesia for surgery (urological and lower limb surgery lasting 2-3 hours, abdominal surgery lasting 45-60 minutes).
Bupivacaine is a long-acting anaesthetic agent of the amide type. Bupivacaine Hydrochloride has a rapid onset of action and long duration. The duration of analgesia in the T10-T12 segments is 2-3 hours.
Bupivacaine Hydrochloride produces a moderate muscular relaxation of the lower extremities lasting 2-2.5 hours. The motor blockade of the abdominal muscles makes the solution suitable for the performance of abdominal surgery lasting 45-60 minutes. The duration of the motor blockade does not exceed the duration of analgesia. The cardiovascular effects of Bupivacaine Hydrochloride are similar to or less than those seen with other spinal agents. Bupivacaine 5 mg/mL with glucose 80 mg/mL is exceptionally well tolerated by all tissues with which it comes in contact.
Sergivell Iso: Bupivacaine hydrochloride is used for the production of local anesthesia by percutaneous infiltration, peripheral nerve block(s), and central neural block (caudal or epidural), that is, for specialist use in situations where prolonged anesthesia is required because sensory nerve block is more marked than motor block, Bupivacaine hydrochloride is especially useful in the relief of pain, e.g. during labor. Bupivacaine hydrochloride is indicated for: Surgical anesthesia in adults and children above 12 years of age.
Management of acute pain in adults and children above 1 year of age.
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