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Each tablet contains: Rosuvastatin (as calcium) 10 mg and 20 mg.
Rosuvastatin is a hydrochloride agent; it is a competitive inhibitor of 3-hydroxy-3methylglutaryl coenzyme A reductase (HMG-CoA reductase), the rate determining enzyme for synthesis HMG-CoA reductase inhibitions (sometimes called "statins") reduce total cholesterol. Low density lipoprotein (LDL)-cholesterol, and very low density lipoprotein (VLDL) cholesterol concentration in plasma. They also tend to reduce triglycerides and to increase high-density lipoprotein (HDL)-cholesterol concentrations. They are considered to exert their hypocholesterolaemic action by stimulating and increase in LDL-receptors on hepatocyte membranes thereby increasing the clearance of LDL from the circulation.
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