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Before treatment initiation, the patient should be placed on a standard cholesterol-lowering diet that should continue during treatment. The dose should be individualized according to the goal of therapy and patient response, using current consensus guidelines.
Rosuvastatin may be given at any time of day, with or without food.
Treatment of hypercholesterolemia: Recommended start dose: 5 or 10 mg orally once daily in both statin naïve or patients switched from another HMG-CoA reductase inhibitor.
A dose adjustment to the next dose level can be made after 4 weeks, if necessary.
Prevention of cardiovascular events: Recommended start dose: 20 mg daily.
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