RiteMED Mefenamic Acid Contraindications

Breastfeeding women, because of the potential for serious adverse reactions in breastfed infants.
Children and adolescents younger than 14 years old.
250 mg: If the patient is allergic to mefenamic acid, aspirin or any other NSAID, or to other ingredients in the product.
If the patient is currently taking aspirin or other NSAIDs.
If the patient has bronchospasm (constriction of air passages of the lungs), angioedema (rapid swelling that occurs in the tissue just below the surface of the skin), nasal polyps or allergic-type reactions after taking aspirin or other NSAIDs.
If the patient had or is suffering from stomach ulcers, bleeding or other stomach problems such as inflammatory bowel disease.
If the patient had diarrhea with this medicine in the past. Diarrhea may recur if the patient takes mefenamic acid again.
If the patient has severe heart, liver or kidney disease.
Bleeding in the brain or other bleeding disorders.
High potassium in the blood.
Dengue fever, since NSAIDs may increase the risk of bleeding.
During the last 3 months of pregnancy.
Right before or after the surgery.
500 mg: Known hypersensitivity to mefenamic acid, aspirin or NSAIDs, or to other ingredients in the product.
Patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactoid reactions to NSAIDs have been reported in such patients.
Patients with a history of gastrointestinal (GI) bleeding or perforation related to previous NSAID therapy.
Patients with previous or active ulceration or chronic inflammation of either the upper or lower GI tract.
Patients with a history of diarrhea with previous mefenamic acid therapy. Diarrhea may recur if mefenamic acid is taken again.
Patients with severe cardiac, hepatic or renal disease.
Cerebrovascular bleeding or other bleeding disorders.
Known hyperkalemia.
Third trimester of pregnancy, because of the risk of premature closure of the fetal ductus arteriosus and delay labor and birth.
Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.