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General Dosing Recommendations: Dosing must be individualized and adjusted according to blood pressure response.
Losartan 50 mg + Amlodipine 5 mg fixed-dose combination (FDC) may be administered in patients whose blood pressure is inadequately controlled with losartan 50 mg or amlodipine 5 mg alone.
Dose titration with the individual drugs is recommended before shifting to the FDC. When clinically appropriate, direct shift from monotherapy to the FDC may be considered.
Usual Oral Dose: 1 tablet of Losartan 50 mg + Amlodipine 5 mg FDC once a day: If blood pressure remains uncontrolled after two weeks, increase the >dose to: Losartan 50 mg and Amlodipine 10 mg once a day or 1 tablet of Losartan 100 mg + Amlodipine 5 mg FDC once a day or 1 tablet of Losartan 100 mg + Amlodipine 10 mg FDC once a day.
Or, as prescribed by a physician.
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