Hypertension: The dose should be adjusted individually. Treatment can be started with 5 mg once daily. Depending on the patient's response, the dose can, where applicable, be decreased to 2.5 mg or increased to 10 mg daily. If necessary another antihypertensive agent may be added. The standard maintenance dose is 5 mg once daily.
Angina pectoris: The dose should be adjusted individually. Treatment should be initiated with 5 mg once daily and, if needed, increased to 10 mg once daily.
Elderly population: Initial treatment with lowest available dose should be considered.
Renal impairment: Dose adjustment is not needed in patients with impaired renal function.
Hepatic impairment: Patients with impaired hepatic function may have elevated plasma concentrations of felodipine and may respond to lower doses (see Precautions).
Paediatric population: There is limited clinical trial experience of the use of felodipine in hypertensive paediatric patients (see Pharmacology: Pharmacodynamics and Pharmacokinetics under Actions).
Method of administration: The tablets should be taken in the morning and be swallowed with water. In order to keep the prolonged-release properties, the tablets must not be divided, crushed or chewed. The tablets can be administered without food or following a light meal not rich in fat or carbohydrate.
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