RiteMED Diclofenac Use In Pregnancy & Lactation

Pregnancy: Pregnancy Category C. Diclofenac is contraindicated for use during the third trimester of pregnancy because of risk of premature closure of the ductus arteriosus and the potential to prolong labor and birth. Caution should be exercised in prescribing diclofenac during the first and second trimesters of pregnancy (see Contraindications).
Inhibition of prostaglandin synthesis may adversely affect pregnancy and/or the embryo-fetal development. Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation after use of a prostaglandin synthesis inhibitor in early pregnancy.
The use of diclofenac, as with any drug known to inhibit cyclooxygenase/prostaglandin synthesis, may impair fertility and is not recommended in women attempting to conceive. Therefore, in women who have difficulties conceiving, or who are undergoing investigation of infertility, withdrawal of diclofenac should be considered.
Lactation: Like other NSAIDs, diclofenac passes into breast milk in small amounts. Therefore diclofenac should not be administered during breast feeding in order to avoid undesirable effects in the infant.