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Signs and Symptoms of Overdose: Pyridoxine Hydrochloride (B6): Prolonged use of large doses of pyridoxine is associated with development of severe peripheral neuropathies.
Cyanocobalamin (B12): Doses greater than 10 mcg daily may produce hematological response in patients with folate deficiency.
Ascorbic Acid: Large doses are reported to cause gastrointestinal disturbances (e.g., diarrhea), hyperoxaluria, formation of renal calcium oxalate calculi. Tolerance may also be induced with prolonged use of large doses.
What to Do When the Patient has Taken More Than the Recommended Usage: If the patient has taken more than the recommended dosage, consult a physician immediately.
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