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Pharmacology: Salmeterol is a selective, long acting (12 hour) beta-2 agonist with a long side chain which binds to the exo-site of the receptor. It produces a longer duration of bronchodilator, lasting for at least 12 hours, than recommended doses of conventional short acting beta-2 agonists. It is used in the treatment of asthma & other forms of diffuse airway obstruction.
Fluticasone Propionate is a synthetic corticosteroid of glucocorticoid family, which has potent anti-inflammatory action within the lungs, resulting in reduced symptoms and exacerbations of asthma. It is stated to exert topical effects on the lungs without systemic effects at usual dose.
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