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Rexulti

Rexulti Drug Interactions

brexpiprazole

Manufacturer:

Otsuka (Philippines)

Distributor:

Otsuka (Philippines)
Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage Patient Counseling Information MIMS Class ATC Classification Regulatory Classification Presentation/Packing
Full Prescribing Info
Drug Interactions
Drugs Having Clinically Important Interactions with Brexpiprazole (Rexulti): See Table 15 for clinically important drug interactions with Brexpiprazole (Rexulti). (See Table 15.)

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Drugs Having No Clinically Important Interactions with Brexpiprazole (Rexulti): Based on pharmacokinetic studies, no dosage adjustment of Brexpiprazole (Rexulti) is required when administered concomitantly with CYP2B6 inhibitors (e.g., ticlopidine) or gastric pH modifiers (e.g., omeprazole). Additionally, no dosage adjustment for substrates of CYP2D6 (e.g., dextromethorphan), CYP3A4 (e.g., lovastatin), CYP2B6 (e.g., bupropion), BCRP (e.g., rosuvastatin), or P-gp (e.g., fexofenadine) is required when administered concomitantly with Brexpiprazole (Rexulti).