Quetiapro Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Quetiapine

Indications/Uses

Schizophrenia & mania associated w/ bipolar disorder.

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Dosage/Direction for Use

Initially 25 mg bid (every 12 hr) on day 1, 50 mg bid (every 12 hr) on day 2, 100 mg bid (every 12 hr) on day 3 & 150 mg bid (every 12 hr) on day 4. Then, adjust to a usual range of 300-450 mg daily in 2 divided doses (every 12 hr).

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity.

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Special Precautions

Contraindicated in patients w/ pre-existing CNS depression or coma, bone marrow suppression, pheochromocytoma or prolactin-dependent tumor. Caution or do not use at all in patients w/ impaired liver, kidney, CV, cerebrovascular & resp function, angle-closure glaucoma, history of jaundice, parkinsonism, DM, hypothyroidism, myasthenia gravis, paralytic ileus, prostatic hyperplasia or urinary retention. Care is required in patients w/ epilepsy or history of seizures. Should be used during pregnancy only if potential benefit justifies potential risk to the fetus. Discontinue nursing while on treatment or discontinue the drug if breastfeeding.

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Use In Pregnancy & Lactation

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Adverse Reactions

Somnolence. Mild asthenia, anxiety, dizziness, myalgia, rhinitis, dyspepsia, increased plasma-triglyceride & cholesterol conc, & reduced plasma-thyroid hormone conc.

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Drug Interactions

Enhanced central effects of other CNS depressants including alcohol. Concomitant use w/ antihypertensives or drugs that prolong QT interval. May antagonize the actions of dopaminergics eg, levodopa. Increased plasma conc w/ potent CYP3A4 inhibitors (eg, erythromycin, fluconazole, itraconazole, & ketoconazole). Decreased plasma conc w/ enzyme inducers (eg, carbamazepine & phenytoin). Increased clearance w/ thioridazine.

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Storage

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Description

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Action

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MIMS Class

Antipsychotics

ATC Classification

N05AH04 - quetiapine ; Belongs to the class of diazepines, oxazepines and thiazepines antipsychotics.

Regulatory Classification

Presentation/Packing

Form

Quetiapro FC tab 100 mg

Packing/Price

60's

Form

Quetiapro FC tab 200 mg

Packing/Price

60's

Form

Quetiapro FC tab 25 mg

Packing/Price

60's

Quetiapro

quetiapine

Manufacturer:

Lloyd

Distributor:

InnoGen Pharmaceuticals