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Each prolonged-release capsule contains Tamsulosin Hydrochloride BP 400 mcg (as modified-release pellets).
Tamsulosin, a selective alpha-1A adrenoceptor blocking agent, exhibits selectivity for alpha-1A receptors in the human prostate. At least, three discrete alpha-1 adrenoceptor subtypes have been identified: alpha-1A, Alpha-1B and alpha-1D; their distribution differs between human organs and tissues. Approximately 70% of the alpha-1 receptors in human prostate are of the alpha-1A subtype.
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