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Prosta-One

Prosta-One Mechanism of Action

finasteride

Manufacturer:

Atoz Pharmaceuticals

Distributor:

One Pharma
Full Prescribing Info
Action
Pharmacology: Pharmacokinetics: Finasteride is absorbed after oral doses and peak plasma concentrations are achieved in 1 to 2 hours. The mean bioavailability has variously been reported as 63% and 80%. It is about 90% bound to plasma protein. Finasteride crosses the blood-brain barrier and is distributed into semen. It is metabolized in the liver primarily by the cytochrome P450 isoenzyme CYP3A4 and excreted in urine and faeces as metabolites. The mean terminal half-life is about 6 hours in patients under 60 years of age but may be prolonged to about 8 hours in those 70 years of age or older.
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