Preva M

Preva M

Manufacturer:

Tirupati

Distributor:

Emcure Pharma
Concise Prescribing Info
Contents
Pregabalin 75 mg, mecobalamin 750 mcg
Indications/Uses
Management of peripheral neuropathy.
Dosage/Direction for Use
Initially 1 cap bid. Patient previously on gabapentin Should have wash-out period of 1 wk prior to start of dosing w/ pregabalin.
Special Precautions
Mecobalamin: Not to be given to patients w/ suspected vit B12 deficiency w/o 1st confirming diagnosis. Monitor blood regularly. Doses >10 mcg daily may produce hematological response in patients w/ folate deficiency; indiscriminate use may mask precise diagnosis. Not to be used for Leber's disease or tobacco amblyopia.
Adverse Reactions
Pregabalin: Dizziness & somnolence; blurred vision, diplopia, increased appetite & wt gain, dry mouth, constipation, vomiting, flatulence, euphoria, confusion, reduced libido, erectile dysfunction, irritability, vertigo, ataxia, tremor, dysarthria, paraesthesia, fatigue, & edema; disturbances of attention, memory, coordination, & gait.
Drug Interactions
Absorption of vit B12 from GIT may be reduced by neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, & colchicine. Serum conc may be decreased w/ OCs. Effect of vit B12 in anemia may be attenuated by parenteral chloramphenicol.
MIMS Class
Drugs for Neuropathic Pain
ATC Classification
N02BF02 - pregabalin ; Belongs to the class of gabapentinoids. Used to relieve pain and other conditions.
Presentation/Packing
Form
Preva M cap
Packing/Price
100's